𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Expression cloning of tumor suppressor genes: A guide for optimists

✍ Scribed by Makoto Noda


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
457 KB
Volume
3
Category
Article
ISSN
0899-1987

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Cloning, sequence, and developmental exp
✍ Sehgal, Anil; Ricks, Sherianne; Keener, Cassie; Boynton, Alton L.; Young, Ronald πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 866 KB

Background: Previously, we reported the isolation of C4-2 as a potential tumor suppressor gene in human brain tumors. To understand the function of this gene, we investigated its molecular characterization and expression during development. Methods: Human fetal brain library screening and 5ЈRACE-PCR

Cloning and expression throughout mouse
✍ Barnaby Cox; Anna-Katerina Hadjantonakis; Jane E. Collins; Anthony I. Magee πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 776 KB

We present the entire sequence of the mouse Fat orthologue (mFat1), a protein of 4,588 amino acids with 34 cadherin repeats, 27 potential N-glycosylation sites, five EGF repeats and a laminin A G-motif in its extracellular domain. A single transmembrane region is followed by a cytoplasmic domain con

Human cell lines engineered for tetracyc
✍ Alexei I. Protopopov; Jinfeng Li; GΓΆsta Winberg; Rinat Z. Gizatullin; Vladimir I πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 310 KB

## Abstract ## Background We modified a tetracycline‐regulated system that can control the activity of individual genes quantitatively and reversibly in transgenic mammals. Despite these advances, there remained one problem in the intensive use of the tet‐system: the limited range of acceptor cell

A novel tumor suppressor gene RhoBTB2 (D
✍ Haiting Mao; Xun Qu; Yongmei Yang; Wenshu Zuo; Ye Bi; Chengjun Zhou; Haipeng Yin πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 159 KB πŸ‘ 1 views

## Abstract RhoBTB2 was isolated recently as a tumor suppressor gene from human chromosome 8p21.3. Although RhoBTB2 was found to be frequently lost in breast cancer lines, expression status of RhoBTB2 in sporadic breast cancer tissues and its clinical and prognostic value, however, remain unclear.

Molecular characterization of a large ho
✍ Farida Latif; Kalman Tory; William S. Modi; Stephen L. Graziano; Gary Gamble; Je πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 844 KB

## Abstract Homozygous deletions are instrumental in the detection and cloning of tumor suppressor genes. We report the isolation and characterization of 39 new single‐copy probes saturating a submicroscopic homozygous deletion detected in the DNA of the small cell lung cancer (SCLC) cell line U202