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Expression cloning of the epithelial sodium channel

✍ Scribed by Canessa, Cecilia M; Horisberger, Jean-Daniel; Schild, Laurent; Rossier, Bernard C


Book ID
109884177
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
445 KB
Volume
48
Category
Article
ISSN
0085-2538

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The high selectivity, low conductance, amiloride-blockable, sodium channel of the mammalian distal nephron (i.e. cortical collecting tubule) is the site of discretionary regulation which allows maintainance of total body sodium balance. In order to understand the physiological events that participat