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Expression and Spectroscopic Analysis of Soluble Nicotinic Acetylcholine Receptor Fragments Derived from the Extracellular Domain of the α-Subunit †

✍ Scribed by Grant, Marianne A.; Gentile, Lisa N.; Shi, Qing-Luo; Pellegrini, Maria; Hawrot, Edward


Book ID
126042794
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
248 KB
Volume
38
Category
Article
ISSN
0006-2960

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Neuronal nicotinic acetylcholine receptors (nAChRs) were expressed in J(enopus laevis oocytes after nuclear injection of complementary deoxyribonucleic acid (eDNA) expression vectors. The two receptor subtypes e4/nc~l and e3/nel were readily distinguishable from one another by ACh sensitivity and de