Somatic mutations of the PTEN tumor supp
✍
Naomi Halachmi; Sarel Halachmi; Ella Evron; Paul Cairns; Kenji Okami; Motoyasu S
📂
Article
📅
1998
🏛
John Wiley and Sons
🌐
English
⚖ 113 KB
👁 3 views
The PTEN (MMAC1/TEP1) tumor suppressor gene was recently isolated and mapped to human chromosome band 10q23. Homozygous deletions and mutations of PTEN were observed in cell lines and sporadic cancers of the breast, kidney, and central nervous system. Germline mutations in PTEN were recently found i