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Expression and significance of TGF-β1/Smad signaling pathway in children with IgA nephropathy

✍ Scribed by Wei Wu; Xiao-Yun Jiang; Qiao-Ling Zhang; Ying Mo; Liang-Zhong Sun; Shu-Mei Chen


Book ID
107659834
Publisher
SP Children’s Hospital, Zhejiang University School of Medicine
Year
2009
Tongue
English
Weight
335 KB
Volume
5
Category
Article
ISSN
1708-8569

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A panel of 6 human glioma cell lines was examined for TGF-␤1 responsiveness. U-178 MG and U-251 MG AgCl1 were significantly inhibited by TGF-␤1, while U-343 MGa 31L and U-343 MGa 35L were potently stimulated to proliferate. TGF-␤1 induced endogenous PAI-1 protein synthesis, Smad binding element/(CAG