Intracellular signaling proteins are very often regulated by site-specific phosphorylation. For example, growth factor receptors in eukaryotic cells contain intrinsic tyrosine kinase activity and use inter- and intra-molecular interactions to recruit and orient potential protein substrates for phosp
β¦ LIBER β¦
Expression and regulation of Sef, a novel signaling inhibitor of receptor tyrosine kinases-mediated signaling in the nervous system
β Scribed by Claudia Grothe; Peter Claus; Kirsten Haastert; Ela Lutwak; Dina Ron
- Book ID
- 116182973
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- German
- Weight
- 797 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0065-1281
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## Abstract Ephrins and Eph receptors are a family of molecules that have been implicated in axonal pathfinding. A unique feature of Bβclass ephrins and Eph receptors is their ability to transmit bidirectional signals in both ephrinβ and Eph receptorβexpressing cells upon cellβcell contact. These s