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Expression and regulation of growth hormone (GH) and prolactin (PRL) receptors in a rat insulin producing cell line (INS-1)

✍ Scribed by Asfari, M.; De, W.; Postel-Vinay, M.-C.; Czernichow, P.


Book ID
122973962
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
715 KB
Volume
107
Category
Article
ISSN
0303-7207

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Increased peptidylarginine deiminase exp
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Insulin and type I insulin-like growth factor (IGF-I) suppressed growth hormone (GH) expression followed by the induction of prolactin (PRL) biosynthesis in MtT/S cells cultured with normal sera. Insulin also increased the peptidylarginine deiminase activity in a dose-dependent manner. The increase