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Expression and Refolding of Recombinant Human α-Tocopherol Transfer Protein Capable of Specific α-Tocopherol Binding

✍ Scribed by Candace Panagabko; Samantha Morley; Steve Neely; Huangshu Lei; Danny Manor; Jeffrey Atkinson


Book ID
115645979
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
234 KB
Volume
24
Category
Article
ISSN
1046-5928

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Using a subtraction-enhanced display technique, we identified a rodent a-tocopherol transfer protein (a-TTP) cDNA which exhibited markedly lower messenger RNA (mRNA) amounts in rat hepatocellular carcinoma (HCC) than in healthy controls. Several lines of evidence have substantiated that abnormal a-T