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Expression and purification of the ligand-binding domain of peroxisome proliferator-activated receptor alpha (PPARα)

✍ Scribed by Mathias Q. Müller; Christian Roth; Norbert Sträter; Andrea Sinz


Book ID
116828872
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
509 KB
Volume
62
Category
Article
ISSN
1046-5928

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## Abstract Peroxisome proliferator‐activated receptor alpha (PPARα) is a member of the nuclear hormone receptor superfamily that can be activated by natural fatty acids and various xenobiotics, including clofibrate. This transcription factor primarily regulates genes involved in lipid metabolism a