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Expression and purification of Mycobacterium tuberculosis ESAT-6 and MPT64 fusion protein and its immunoprophylactic potential in mouse model

✍ Scribed by Yinlan Bai; Ying Xue; Hui Gao; Limei Wang; Tianbing Ding; Wentao Bai; Ailin Fan; Jianfang Zhang; Qunxing An; Zhikai Xu


Book ID
116828736
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
455 KB
Volume
59
Category
Article
ISSN
1046-5928

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## Abstract MPT64, a secreted protein of __Mycobacterium tuberculosis__ (MTB), stimulates the immune reactions within cells and is a protective antigen that is lost by the bacilli Calmette–GuΓ©rin (BCG) vaccine during propagation. To minimize the toxicity caused by MTB, we used the __MPT64__ gene en