✦ LIBER ✦

Expression and mutation analysis of the p53 gene in uterine papillary serous carcinoma

✍ Scribed by Stephanie A. King; Amy A. Adas; Virginia A. Livolsi; Hiroyuki Takahashi; Kian Behbakht; Patricia McGovern; Ivor Benjamin; Stephen C. Rubin; Jeff Boyd

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 950 KB
Volume: 75
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19950601)75:11<2700::aid-cncr2820751110>3.0.co;2-i

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Uterine papillary serous carcinoma after

Uterine papillary serous carcinoma after radiation therapy for carcinoma of the cervix

✍ Vinita Parkash; Maria L. Carcangiu 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 818 KB

This article describes the clinicopathologic features of six cases of uterine papillary serous carcinoma (UPSC), which developed several years after radiation therapy (RT) for cervical carcinoma. The possible etiologic role of radiation is discussed, and the literature on endometrial carcinomas deve

Relationship between E-cadherin gene mut

Relationship between E-cadherin gene mutation and p53 gene mutation, p53 accumulation, Bcl-2 expression and Ki-67 staining in diffuse-type gastric carcinoma

✍ Elena Fricke; Gisela Keller; Ingrid Becker; Erika Rosivatz; Christina Schott; Su 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 440 KB

## Abstract E‐cadherin mutations are found in 50% of diffuse‐type gastric carcinoma, but not in intestinal gastric carcinoma. Because cell–cell adhesion mediated by E‐cadherin plays an important role in epithelial cell survival, E‐cadherin mutations could alter the apoptotic behavior of tumor cells

The frequency of p53, k-ras mutations, a

The frequency of p53, k-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma : Evidence of distinct molecular genetic pathways

✍ Sigurd F. Lax; Brian Kendall; Hironori Tashiro; Robbert J. C. Slebos; Lora Hedri 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 398 KB 👁 2 views

## BACKGROUND. The two most common types of uterine endometrial carcinoma, endometrioid (UEC) and serous (USC), differ in their histopathologic appearance and biologic behavior. Recent studies suggest that these differences may be associated with distinct molecular genetic alterations. ## METHODS.

Impaired BAX protein expression in breas

Impaired BAX protein expression in breast cancer: Mutational analysis of the BAX and the p53 gene

✍ Isrid Sturm; Sarantos Papadopoulos; Timo Hillebrand; Thomas Benter; Hans-Joachim 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 85 KB 👁 2 views

Amplification of c-erbB2 oncogene : A ma

Amplification of c-erbB2 oncogene : A major prognostic indicator in uterine serous papillary carcinoma

✍ Alessandro D. Santin; Stefania Bellone; Sue Van Stedum; Wendy Bushen; Michela Pa 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB

## Abstract ## BACKGROUND Overexpression of the epidermal growth factor type II receptor HER‐2/__neu__ has been associated with resistance to chemotherapy and poor survival in several human tumors. In the current study, the authors have determined the frequency and clinical significance of HER‐2/_

Functional analysis of p53 gene and the

Functional analysis of p53 gene and the prognostic impact of dominant-negative p53 mutation in endometrial cancer

✍ Noriaki Sakuragi; Hidemichi Watari; Yasuhiko Ebina; Ritsu Yamamoto; Eric Steiner 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 182 KB 👁 1 views

## Abstract In addition to the loss of function, mutant p53 can possess a dominant‐negative effect on wild‐type p53 and may also exert gain‐of‐function activity. It is not clear whether the functional status of __p53__ mutation contributes to differences in outcome in endometrial cancer. We collect