Expression and membrane integration of SARS-CoV M protein
✍ Scribed by Hsin-Chieh Ma; Chiu-Ping Fang; Yi-Ching Hsieh; Shih-Chi Chen; Hui-Chun Li; Shih-Yen Lo
- Publisher
- BioMed Central
- Year
- 2008
- Tongue
- English
- Weight
- 472 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1021-7770
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## Abstract Severe acute respiratory syndrome coronavirus (SARS‐CoV) infects many organs, such as lung, liver, and immune organs and causes life‐threatening atypical pneumonia, SARS causes high morbidity and mortality rates. The molecular mechanism of SARS pathogenesis remains elusive. Inflammatory
## Abstract ## Background Severe acute respiratory syndrome (SARS) is caused by a novel coronavirus (SARS‐CoV). It is an enveloped, single‐stranded, plus‐sense RNA virus with a genome of ∼30 kb. The structural proteins E, M and N of SARS‐CoV play important roles during host cell entry and viral mo