Expression and localization of thrombomodulin in preneoplastic bronchial lesions and in lung cancer
✍ Scribed by Edina Tolnay; Thorsten Wiethege; Klaus-Michael Müller
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 526 KB
- Volume
- 430
- Category
- Article
- ISSN
- 1432-2307
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Cytochrome P450 (CYP) 2A5 is involved in the metabolism of carcinogens like aflatoxin B1 and N-nitrosodiethylamine (NDEA), and CYP2A5 levels are increased in some pathological states of the liver (e.g., infectious hepatitis and porphyria). We analyzed the expression of CYP2A5 during experimental liv
## Abstract Thrombomodulin (TM) plays a role in coagulation, inflammation, and cell adhesion. Reduction of TM expression plays an important role in the tumor metastatic process; however, insufficient information is available regarding the expression of TM in nonsmall cell lung cancer (NSCLC). Sixty