Expression and localization of membrane-type-1 matrix metalloproteinase, CD 44, and laminin-5γ2 chain during colorectal carcinoma tumor progression

Predictive value of laminin-5 and membra

Predictive value of laminin-5 and membrane type 1-matrix metalloproteinase expression for cervical lymph node metastasis in T1 and T2 squamous cell carcinomas of the tongue and floor of the mouth

✍ Kenji Kawano; Shigetaka Yanagisawa 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 331 KB 👁 1 views

Background. Laminin-5 (Ln-5) cleaved by membrane type 1-matrix metalloproteinase (MT1-MMP) enhances the migration of tumor cells. The purpose of this study was to determine whether or not enhanced expression of both Ln-5 and MT1-MMP was associated with lymph node metastasis in patients with T1 and T