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Expression and inducibility of UDP-glucuronosyltransferases 1-naphthol in human cultured hepatocytes and hepatocarcinoma cell lines

โœ Scribed by Amr Abid; Nicole Sabolovic; Jacques Magdalou

Book ID
117175009
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
896 KB
Volume
60
Category
Article
ISSN
0024-3205

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โœ A. Abid; N. Sabolovic; J. Magdalou ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer ๐ŸŒ English โš– 712 KB

Two human hepatoma cell lines, KYN-2 and Mz-Hep-1 were characterized in terms of glucuronidation capacity and inducibility of cytochrome P4501A1/1A2 and several UDP-glucuronosyltransferases (UGTs). Cytochrome P4501A1/1A2 activity was measured using 7-ethoxyresorufin and that of UGTs with 16 differen