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Expression and immunogenicity of the Plasmodium falciparum circumsporozoite protein: The role of GPI signal sequence

✍ Scribed by Olga J.A.E Ophorst; Katarina Radošević; Krista Ouwehand; Wouter van Beem; Ratna Mintardjo; Jeroen Sijtsma; Jorn Kaspers; Arjen Companjen; Lennart Holterman; Jaap Goudsmit; Menzo J.E. Havenga


Book ID
116959398
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
776 KB
Volume
25
Category
Article
ISSN
0264-410X

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Plasmodium falciparum: recombinant bacul
✍ Paul Jacobs; Marc Massaer; Michel Heinderyckx; Fabienne Milican; Pascal Gilles; 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 713 KB

The DNA coding for the circumsporozoite protein (CPS) of Plasmodium falciparum has been cloned into the baculovirus expression vector pAcYM1 and expressed in Spodoptera frugiperda (Sf9) insect cells. Three DNA constructs have been made: the first one directs the synthesis of the complete CSP (aa 1-4