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Expression and function of the chemokine, CXCL13, and its receptor, CXCR5, in AIDS-associated non-Hodgkin's lymphoma

✍ Scribed by DP Widney, D Gui, JW Said, EC Breen, R Detels…


Book ID
120697237
Publisher
BioMed Central
Year
2009
Tongue
English
Weight
65 KB
Volume
4
Category
Article
ISSN
1750-9378

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CD40 is a membrane glycoprotein expressed on normal and neoplastic B lymphocytes. Stimulation through CD40 regulates important cellular functions, but the effects depend on its membrane density. While extensive studies have characterized CD40 in non-Hodgkin lymphomas of immunocompetent individuals,