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Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes

✍ Scribed by Havran, Wendy L.; Poenie, Martin; Kimura, John; Tsien, Roger; Weiss, Arthur; Allison, James P.


Book ID
109751185
Publisher
Nature Publishing Group
Year
1987
Tongue
English
Weight
469 KB
Volume
330
Category
Article
ISSN
0028-0836

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## Abstract In normal mice, more than 10% of thymocytes in the CD4^+^CD8^–^ and CD4^–^CD8^+^ single‐positive (SP) subsets express a medium level of CD3 on the cell surface. However, the fate of CD3^medium^ cells is unclear. The CD3^medium^ SP subpopulations might contain (i) cells in an immature st