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Expression and function of small heat shock protein genes during Xenopus development

✍ Scribed by John J Heikkila

Book ID
116881039
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
156 KB
Volume
14
Category
Article
ISSN
1084-9521

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## Abstract Small heat shock proteins (shsps) are molecular chaperones that are inducible by environmental stress such as elevated temperature or exposure to heavy metals or arsenate. Recent interest in shsps has been propelled by the finding that shsp synthesis or mutations are associated with var

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## Abstract Summary: We examined the effect of histone deacetylase inhibitors (HDIs), trichostatin A (TSA), valproic acid (VPA), and sodium butyrate (NaB) on heat shock protein (hsp) gene expression during early __Xenopus laevis__ development. HDIs enhance histone acetylation and result in the reli