## Abstract The inappropriate activation of one or more members of the ErbB family of receptor tyrosine kinases [ErbB‐1 (EGFR), ErbB‐2, ErbB‐3, ErbB‐4] has been linked with oncogenesis. ErbB‐2 is frequently coexpressed with ErbB‐3 in breast cancer cells and in the presence of the ligand heregulin (
✦ LIBER ✦
Expression and function of heregulin-α and its receptors in the mouse mammary gland
✍ Scribed by LiJing Geng; QingZhang Li
- Book ID
- 107349829
- Publisher
- Science in China Press (SCP)
- Year
- 2010
- Tongue
- English
- Weight
- 931 KB
- Volume
- 53
- Category
- Article
- ISSN
- 1674-7305
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## Abstract Mouse mammary epithelial cells (HC‐11) and mammary tissues were analyzed for developmental changes in circadian clock, cellular proliferation, and differentiation marker genes. Expression of the clock genes __Per1__ and __Bmal1__ were elevated in differentiated HC‐11 cells, whereas __Pe