Expression and function of CD2 during murine thymocyt
โ Scribed by Hideo Yagita; Jun-Ichi Asakawa; Shigeru Tansyo; Tetsuya Nakamura; Sonoko Habu; Ko Okumura
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 762 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0014-2980
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## Expression and ontogeny of murine CD2* CD2 was first defined as the erythrocyte rosetting protein on the surface of human T cells. Recently, the rat and murine homologues have been identified by cDNA cloning. In this report we demonstrate that CD2 is expressed on the surface of most adult murin
Co-stimulatory signals mediated by the interaction of B7-1/B7-2 with CD28 are important for the activation of CD4 + T cells stimulated with antigen on antigen-presenting cells. There are controversies about the expression and function of B7-1/B7-2 on CD4 + T cells. The aim of this study was to analy