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Expression and enzymatic activities of cytochrome P450 species in human hepatocytes

✍ Scribed by D. Runge; D.M. Runge; D. Jäger; V.E. Kostrubsky; S.C. Strom; G.K. Michalopoulos; W.E. Fleig

Book ID
119526492
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
95 KB
Volume
32
Category
Article
ISSN
0168-8278

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The aim of this study was to test suitable culture conditions for maintaining normal cellular cytoarchitecture and inducibility of P450 enzymes in primary cultures of human hepatocytes by prototypical inducers. The selectivity and sensitivity of a sandwich culture system were determined by treating