Gain of chromosome arm 8q is a frequent genetic alteration in breast and prostate cancer. Two amplified subregions, 8q21 and 8q23-24, have been identified with comparative genomic hybridization (CGH). We have recently demonstrated that the EIF3S3 (eIF3-p40) gene, located at 8q23, is often amplified
✦ LIBER ✦
Expression and copy number analysis of TRPS1, EIF3S3 and MYC genes in breast and prostate cancer
✍ Scribed by Savinainen, K J; Linja, M J; Saramäki, O R; Tammela, T L J; Chang, G T G; Brinkmann, A O; Visakorpi, T
- Book ID
- 109997969
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 133 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0007-0920
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## Abstract Triple‐negative breast cancer (TNBC) is defined by a lack of expression of estrogen, progesterone, and HER2 receptors, and genetically most of them fall into the basal subgroup of breast cancer. The important issue of TNBC is poorer clinical outcome and absence of effective targeted the