The sequence encoding the truncated core protein (amino acids 1-98) of hepatitis C virus (HCc) was expressed in E. coli for production of HCc (1-98) , or fused with the truncated core antigen (HBcAg) and segments from the preS1 and preS2 regions from hepatitis B virus (HBV) for production of HBcPreS
Expression and characterization of hepatitis C virus core protein fused to hepatitis B virus core antigen
β Scribed by Li Yang; Chunlin Wang; Yuan Wang; Guangdi Li
- Publisher
- Science in China Press (SCP)
- Year
- 1999
- Tongue
- English
- Weight
- 942 KB
- Volume
- 42
- Category
- Article
- ISSN
- 1674-7305
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## Abstract The prevalence of serum HBV DNA in individuals positive for antiβHBc alone was determined by the polymerase chain reaction in two groups with endemic HBV infection from Canton (group A) and Hainan (group B), provinces of China. Twentyβone out of 294 individuals in group A (7.2%) and 193
DNA immunization has been used to induce either humoral or cellular immune responses against many antigens, including hepatitis C virus (HCV). In addition, DNA immunizations can be enhanced or modulated at the nucleotide level. Genetic immunizations were examined in BALB/c mice through the use of pl