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Expression and biological role of the prostaglandin D synthase/SOX9 pathway in human ovarian cancer cells

✍ Scribed by Safia Malki; Frédéric Bibeau; Cécile Notarnicola; Sylvie Roques; Philippe Berta; Francis Poulat; Brigitte Boizet-Bonhoure

Book ID
116334453
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
579 KB
Volume
255
Category
Article
ISSN
0304-3835

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✍ Bing Su; Ming Guan; Jing Xia; Yuan Lu 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 118 KB

## Abstract Lipocalin‐type prostaglandin D synthase (LPGDS; PGH~2~D‐isomerase; EC 5.3.99.2) is a bifunctional protein first identified in the mammalian brain. It acts as a PGD~2~‐producing enzyme and a retinoid transporter. Recent studies have shown that LPGDS is anomalously expressed in ovarian tu