Expression and biochemical characterization of thePlasmodium falciparumprotein kinase A catalytic subunit
✍ Scribed by Nathalie Wurtz; Boris Pastorino; Lionel Almeras; Sébastien Briolant; Claude Villard; Daniel Parzy
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 210 KB
- Volume
- 104
- Category
- Article
- ISSN
- 1432-1955
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Using the cre-loxP recombination system, we generated a line of mice expressing a constitutively active catalytic subunit of Protein Kinase A (PKA) in a temporally and spatially regulated fashion. In the absence of cre recombinase the modified catalytic subunit allele is functionally silent, but aft
## Abstract ## Background __PRKACA__ and __PRKACB__ are genes encoding the cAMP‐dependent protein kinase A (PKA) catalytic subunits alpha and beta, respectively. PKA is known to be involved in embryonic development, as it downregulates the Hedgehog (Hh) signaling pathway, which is critical to norm