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Expression and analysis of the Epstein-Barr virus BARF1-encoded protein from a tetracycline-regulatable adenovirus system

โœ Scribed by M. de Turenne-Tessier; P. Jolicoeur; J.M. Middeldorp; T. Ooka

Book ID
116967485
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
307 KB
Volume
109
Category
Article
ISSN
0168-1702

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The BARF1 gene is located in the BamHI-A fragment of the Epstein-Barr virus (EBV) genome, encodes 221 amino acids, and has activity as an oncogene. Several reports have demonstrated that BARF1 is expressed in the tissues of various EBV-associated epithelioid malignancies. However,BARF1 is thought to

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Two genes encoding the latent membrane protein 1 (LMP1) of the Epstein-Barr virus (EBV) were isolated from a single case of Hodgkin's disease (HD) and were tested for their biological activities. The LMP1 gene from the Reed-Sternberg cells contained point mutations relative to the prototype LMP1 gen