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Expression analysis of the gene encoding for the U-box-type ubiquitin ligase UBE4A in human tissues

โœ Scribed by Gianmarco Contino; Francesca Amati; Sabina Pucci; Eugenio Pontieri; Flavia Pichiorri; Antonio Novelli; Annalisa Botta; Ruggiero Mango; Anna Maria Nardone; Federica Carla Sangiuolo; Gennaro Citro; Luigi Giusto Spagnoli; Giuseppe Novelli


Book ID
116506607
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
342 KB
Volume
328
Category
Article
ISSN
0378-1119

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We have investigated the endogenous expression of menin, a protein encoded by the gene mutated in multiple endocrine neoplasia type 1 (MEN1). Western blot analysis showed strong expression of menin as a 68 kDa protein in all of 7 human and primate cell lines tested. In a panel of 12 fetal human tiss