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Expression analysis of mRNA in formalin-fixed, paraffin-embedded archival tissues by mRNA in situ hybridization

✍ Scribed by Ralf T. Henke; Sung Eun Kim; Anirban Maitra; Soonmyung Paik; Anton Wellstein


Book ID
116986664
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
378 KB
Volume
38
Category
Article
ISSN
1046-2023

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Analysis of gene expression can provide important information related to prognostic or predictive factors in clinical work. Analysis of DNA or RNA isolated from formalin fixed and paraffin-embedded tissue is generally accepted to be difficult due to degradation and crosslinking. Factors affecting mR