Exposure of p19 matrix protein of human T-cell leukemia virus type I (HTLV-I) on the surface of MOLT-4#8 cells after virus adsorption
β Scribed by H. Akari; M. J. Kuroda; T. Shinjo; M. A. El-Farrash; S. Harada
- Book ID
- 105154258
- Publisher
- Springer Vienna
- Year
- 1994
- Tongue
- English
- Weight
- 562 KB
- Volume
- 136
- Category
- Article
- ISSN
- 1432-8798
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## Abstract In order to clarify the cellular tropism of human Tβcell leukemia virus type I (HTLVβI) and the effects of HTLVβI infection on Tβcell functions, we investigated the infectiousness of HTLVβI on T cells bearing Tβcell receptor (TCR) Ξ³Ξ΄ and functional alterations of the HTLVβIβinfected TCR
## Sixteen monoclonal antibodies (MAbs ) against TA34 antigen found on the surface of human T-cell leukemia virus type-I (HTLV-I) infected cells were prepared. These MAbs and one previously prepared anti-TA34 MAb (TAG34) recognized 34-kDa peptide not only in HTLV-I-infected cells, but also in cell