Azabicyclo[X.Y.0] alkane amino acids are rigid dipeptide b-turn mimetics with great potential applications for drug discovery. The lack of efficient methods to synthesize these compounds is a major bottleneck in this field. Herein we report an efficient approach to the enantiopure synthesis of (3S,6
✦ LIBER ✦
Exploring the Unique Reactivity of Diazoesters: An Efficient Approach to Chiral β-Amino Acids
✍ Scribed by Trost, Barry M.; Malhotra, Sushant; Ellerbrock, Pascal
- Book ID
- 118270974
- Publisher
- American Chemical Society
- Year
- 2013
- Tongue
- English
- Weight
- 398 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1523-7060
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