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Exploring the Energy Landscape through Ancestral Proteins

✍ Scribed by An, Shion; Hart, Kathryn M.; Marqusee, Susan


Book ID
123185195
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
51 KB
Volume
106
Category
Article
ISSN
0006-3495

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## Abstract The evolution of our physics‐based computational methods for determining protein conformation without the introduction of secondary‐structure predictions, homology modeling, threading, or fragment coupling is described. Initial use of a hard‐sphere potential captured much of the structu