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Exploring metabolic pathways in genome-scale networks via generating flux modes

โœ Scribed by Rezola, A.; de Figueiredo, L. F.; Brock, M.; Pey, J.; Podhorski, A.; Wittmann, C.; Schuster, S.; Bockmayr, A.; Planes, F. J.


Book ID
118245572
Publisher
Oxford University Press
Year
2010
Tongue
English
Weight
375 KB
Volume
27
Category
Article
ISSN
1367-4803

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Genome-scale metabolic networks can be characterized by a set of systemically independent and unique extreme pathways. These extreme pathways span a convex, high-dimensional space that circumscribes all potential steady-state #ux distributions achievable by the de"ned metabolic network. Genome-scale