✦ LIBER ✦

Exploring development and disease through germ-line genetic engineering in the mouse

✍ Scribed by Reeves, Roger H.

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 96 KB
Volume: 253
Category: Article
ISSN: 0003-276X
DOI: 10.1002/(sici)1097-0185(199802)253:1<19::aid-ar9>3.0.co;2-9

No coin nor oath required. For personal study only.

✦ Synopsis

New developments in mouse genetics have transformed the field of genetics from a reactive to a proactive science. Current technologies in transgenesis, chromosome engineering, and saturation mutagenesis are introduced. These approaches permit the creation of new mutations and consequent mutant phenotypes that facilitate both the understanding of functions of existing genes and the search for previously unidentifed genes affecting important phenotypes in all mammals.

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