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Exploratory laparotomy and splenectomy in the diagnosis of Hodgkin's disease in children

✍ Scribed by B. A. Kolygin; G. A. Fedoreev


Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
287 KB
Volume
8
Category
Article
ISSN
0022-4790

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✦ Synopsis


Abstract

Thirty‐three children with histologically proved Hodgkin's disease underwent exploratory laparotomy with splenectomy and biopsy of lumbar lymph nodes, liver, and bone marrow. In 13 patients (39%) the lesion of spleen and/or splenic hilar lymph nodes was diagnosed. The involvement of spleen was mostly found in patients with mixed cellularity type, in the presence of systemic symptoms (β€œB”), and in the biological stage β€œb.” Involvement of the liver was found in 1 patient, of the hepatic hilar lymph nodes in 3 patients, and of the bone marrow in 4 patients. The lymphographic and histologic data as regards lumbar lymph nodes coincided in 65% of cases. After operation the stage of the disease was changed in 48% patients. The early and late complications were not numerous.


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Between 1969 and 1983, 123 patients with Hodgkin's disease underwent a staging laparotomy. The stages of 34 (27%) patients were changed by laparatomy. Twenty-nine patients (23 %) were upstaged, five (4%) downstaged. The most considerable change was found in stage 111. The accuracy of preoperative l