Exploratory laparotomy and splenectomy in the diagnosis of Hodgkin's disease in children
β Scribed by B. A. Kolygin; G. A. Fedoreev
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 287 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0022-4790
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β¦ Synopsis
Abstract
Thirtyβthree children with histologically proved Hodgkin's disease underwent exploratory laparotomy with splenectomy and biopsy of lumbar lymph nodes, liver, and bone marrow. In 13 patients (39%) the lesion of spleen and/or splenic hilar lymph nodes was diagnosed. The involvement of spleen was mostly found in patients with mixed cellularity type, in the presence of systemic symptoms (βBβ), and in the biological stage βb.β Involvement of the liver was found in 1 patient, of the hepatic hilar lymph nodes in 3 patients, and of the bone marrow in 4 patients. The lymphographic and histologic data as regards lumbar lymph nodes coincided in 65% of cases. After operation the stage of the disease was changed in 48% patients. The early and late complications were not numerous.
π SIMILAR VOLUMES
Between 1969 and 1983, 123 patients with Hodgkin's disease underwent a staging laparotomy. The stages of 34 (27%) patients were changed by laparatomy. Twenty-nine patients (23 %) were upstaged, five (4%) downstaged. The most considerable change was found in stage 111. The accuracy of preoperative l