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Exploration of the mechanism for LPFFD inhibiting the formation of β-sheet conformation of Aβ(1–42) in water

✍ Scribed by Cao Yang; Xiaolei Zhu; Jinyu Li; Rongwei Shi

Book ID: 106240172
Publisher: Springer-Verlag
Year: 2010
Tongue: English
Weight: 529 KB
Volume: 16
Category: Article
ISSN: 1610-2940
DOI: 10.1007/s00894-009-0594-y

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## Abstract CD and infrared spectroscopic studies were performed on (i) the inhibitory effects of equimolar quantities of LPFFD‐OH and LPYFD‐NH~2~ on the time‐dependent aggregation of amyloid β‐protein (Aβ) (1–42) and (ii) the β‐sheet‐breaker effects of two‐fold molar excess of the pentapeptides on

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