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Exploration of the binding mode of α/β-type small acid soluble proteins (SASPs) with DNA

✍ Scribed by Yan Ge; Jiayan Wu; Jingfa Xiao; Jun Yu

Book ID: 106240537
Publisher: Springer-Verlag
Year: 2011
Tongue: English
Weight: 804 KB
Volume: 17
Category: Article
ISSN: 1610-2940
DOI: 10.1007/s00894-011-1007-6

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## Abstract Insulin‐like growth factor 1 (IGF‐1) and its major binding protein, IGF binding protein 3 (IGFBP‐3) are implicated in lung cancer and other malignancies. We have previously shown that the combination of three major antioxidants [β‐carotene (BC), α‐tocopherol (AT) and ascorbic acid (AA)]