Exploiting the Self-Assembly Strategy for the Design of Selective CuII Ion Chemosensors

✍ Scribed by Patrizia Grandini; Fabrizio Mancin; Paolo Tecilla; Paolo Scrimin; Umberto Tonellato

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 129 KB
• Volume: 38
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/(sici)1521-3773(19991018)38:20<3061::aid-anie3061>3.0.co;2-a

✦ Synopsis

Chemosensors, small abiotic molecules that signal the presence of analytes, typically combine two components: a recognition site that binds the target substrate and a readout system that signals binding. [1] In the case of metal ion sensors the recognition site is a metal-chelating molecule designed to bind the target ion selectively and the readout system is very often a fluorophore. The two components are usually covalently linked through a spacer and the complexation of the metal ion results in a variation of the position and/or intensity of the emission band of the fluorophore. With this set-up a large number of molecular sensors has been devised for the detection of alkali and transition metal ions in solution. [1] Among the latter group, Cu II has attracted Abel, F. G. A. Stone, G. Wilkinson), Pergamon, Oxford, 1995, chap. 7.3, p. 741, and references therein. graphic data (excluding structure factors) for the structures reported in this paper have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication nos. CCDC-115339 and 115340. Copies of the data can be obtained free of charge on application to CCDC,