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Exploiting protein flexibility to predict the location of allosteric sites

✍ Scribed by Alejandro Panjkovich, Xavier Daura


Book ID
120675840
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
459 KB
Volume
13
Category
Article
ISSN
1471-2105

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Multiple-solvent crystal structure determination (MSCS) allows the position and orientation of bound solvent fragments to be identified by determining the structure of protein crystals soaked in organic solvents. We have extended this technique by the determination of high-resolution crystal structu