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Experiments on the biological activities of various fractions of the folic acid antagonist “X-methyl” folic acid

✍ Scribed by E.L.R. Stokstad; O. Okinaka; G. Kusano


Book ID
115706877
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
460 KB
Volume
251
Category
Article
ISSN
0003-9861

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✍ Samuel Charache; Paul T. Condit; Allan H. Levy; Stewart R. Humphreys; Abraham Go 📂 Article 📅 1960 🏛 John Wiley and Sons 🌐 English ⚖ 357 KB 👁 2 views

OLIC ACID administered to mice 1 hour be-F fore a lethal dose of aminopterin prevents death due to the drug.8 A nonlethal "priming" dose (LD,) of aminopterin abolishes this protective effect.' Simultaneous administration of folinic acid (5-formyl-5,6,7,8-tetrahydropteroylglutamic acid) also protects