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Experimentally induced phenylketonuria. III. Inhibitors of phenylalanine hydroxylase related to esculetin

✍ Scribed by DeGraw, Joseph I.; Cory, Michael; Skinner, Wilfred A.; Theisen, Myna C.; Mitoma, Chozo


Book ID
126884067
Publisher
American Chemical Society
Year
1968
Tongue
English
Weight
261 KB
Volume
11
Category
Article
ISSN
0022-2623

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A total of 252 chromosomes from 126 patients with phenylalanine hydroxylase (PAH) deficiencies were analyzed for both mutant genotypes and restriction fragment length polymorphism (RFLP) haplotypes at the PAH locus. The mutant genes studied originated either from Western Europe (116 alleles) or from