Experimental study of lumbar facet degeneration in monkeys
β Scribed by S. Ogata; S. Goto; M. Kurihara; R. Shimo
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 843 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0341-2695
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β¦ Synopsis
Experiments were carried out in young adult monkeys to determine the influence of mechanical stress on degeneration of the lumbar facet joints. Eleven monkeys were used and divided into four groups, the control, upper lumbar laminectomy, discectomy and discectomy 4-rotation. The monkeys were given fluorochrome agents once a week. After sacrifice, undemineralised sections were studied under fluorescence microscopy. Contact microradiographs were also made. After laminectomy, subperiosteal bony proliferation was seen on the external surface o f the superior and inferior articular processes. After discectomy there was localised bony proliferation on the anterior aspect of the superior articular processes. In the group with discectomy 4-rotation there was evidence of additional proliferation of the calcified cartilage zone at the insertion of the ligamentum flavum which had remodelled to bony tissue. We conclude that rotational stresses are mostly responsible for the development of spinal stenosis.
R~sum~. Une skrie d'expbriences a ~tk r~alis~e afln de mieux connaitre le r6le des contraintes mbcaniques dans la dbg~n~rescence des articulations inter-vertObrales. Un groupe de 11 singes jeunes, mais matures, a ~tk divis~ en quatre sous-groupes: 1. sous-groupe de contr61e, 2. sous-groupe avec laminectomie lombaire haute, 3. sous-groupe ayant subi une discectomie lombaire, 4. sous-groupe soumis gt une discectomie et gl une contrainte rotatoire.
Une injection d'un fluorochrome a ktk pratiquke une fois par semaine. AprOs sacrifice, des coupes non dOminkralis~es ont btk faites et ktudikes en lumiOre ultra-violette. Des microradiographies ont kgale-
Offprint requests to: S. Ogata ment kt~ pratiqukes. Dans le sous-groupe laminectomie, une apposition osseuse sous-pkrios@e des apophyses articulaires supbrieure et inf~rieure fut de rOgle d la face externe, mais non du c6tk faisant face au canal rachidien. Dans le sous-groupe discectomie, une formation osseuse localis~e, sitube d la partie antkrieure de l'apophyse articulaire supkrieure, fut notbe. Enfin, dans le sous-groupe discectomie 4-rotation on observa, en plus des changements notks dans le sous-groupe prkcbdent, une large zone de calcification cartilagineuse avec bvidence d'ossification enchondrale d l'insertion du ligament jaune. Sur la base de ces rksultats nous concluons que ce sont surtout les contraintes rotatoires qui sont responsables de la stknose rachidienne.
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