Experimental results and physico-chemical aspects of supercritical fluid chromatography with carbon dioxide as the mobile phase

✍ Scribed by D. Bartmann; G.M. Schneider

• Publisher: Elsevier Science
• Year: 1973
• Tongue: English
• Weight: 860 KB
• Volume: 83
• Category: Article
• ISSN: 1873-3778
• DOI: 10.1016/s0021-9673(00)97034-1

✦ Synopsis

In fluid chromatography, compressed fluids at temperatures in the critical range are used as mobile phases, particularly for the separation of substances with low migration rates and/or low thermal stabilities. Some results of isobaric and pressure-programmed separations with supercritical CO2 as the mobile phase are presented. These results are discussed with respect to the phase behaviour and the transport properties of fluid CO2 mixtures at elevated pressures and compared with the results of other workers. The experimental HETP values agree fairly well with data calculated from a modified Van Deemter equation with dimensionless numbers.

l At a critical point, two phases in equilibrium become identical. The line that connects the critical points of all binary mixtures of a system in the p-T-x spncc is the critical curve (X = mole fraction). The phase equilibria and critical phenomena can bc advantageously discussed with the aid of p(T) projections of these critical curves (the so-called critical p(T) locus curves).