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Experimental models of acute pancreatitis

✍ Scribed by Mr A. K. Banerjee; S. W. Galloway; A. N. Kingsnorth

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
860 KB
Volume
81
Category
Article
ISSN
0007-1323

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✦ Synopsis

Abstract

Various models of experimental acute pancreatitis are described. An ideal model would be reproducible, have a similar natural history to that of the human disease and a similar response to treatment. Furthermore, it should be relatively cheap and simple. Few, if any, of the available experimental models completely satisfy these criteria. The appropriate choice of model is discussed, as are possible future developments in this field.

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## Abstract ## Background Platelets not only control thrombosis and haemostasis but may also regulate inflammatory processes. Acute pancreatitis (AP) is characterized by changes in both coagulation and proinflammatory activities. The role of platelets in AP is not yet known. ## Methods AP was in