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Experimental modelling of the synthesis of imidazole rings in biological systems: A possible mechanism for iron-induced diseases of the nucleotide synthesis

✍ Scribed by Franz Renz; Miroslav Boca; Peter Baran; Roman Boca; Usama El-Ayaana; Guido Kickelbick; Yutaka Fukuda; Wolfgang Linert


Book ID
108405035
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
66 KB
Volume
67
Category
Article
ISSN
0162-0134

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To confirm the natural relative stereochemistry of the ABC-ring of goniodomin A (1), the corresponding three stereoisomeric compounds, (2R,5S,6S,7S,9S,11R,15S)-, (2R,5S,6S,7R,9R,11S,15R)-, and (2R,5S,6S,7R,9R,11R,15S)-isomers (2, 3, and 5, respectively), were stereoselectively synthesized using a No