Experimental model of doxorubicin extravasation in the mouse
β Scribed by Robert T. Dorr; David S. Alberts; Hsiao-Sheng George Chen
- Book ID
- 119085783
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 1010 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0160-5402
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π SIMILAR VOLUMES
Extravasation of doxorubicin and its derivative epirubicin, cause severe progressive tissue necrosis that requires early excision of all affected tissues. Doxorubicin and epirubicin are autofluorescent and this characteristic can be used to demonstrate and delineate extravasation by the aid of fluor
Application of subatmospheric pressure to sites injected with doxorubicin prevented ulcer formation in treated sites (0 ulcers/16 sites) compared to control wounds (10 ulcers/16 sites) in a pig model. Background and Objectives: Extravasation of doxorubicin hydrochloride (Adriamycin) frequently cause