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Experimental evidence that ornithine and homocitrulline disrupt energy metabolism in brain of young rats

✍ Scribed by Carolina Maso Viegas; Ângela Zanatta; Lisiane Aurélio Knebel; Patrícia Fernanda Schuck; Anelise Miotti Tonin; Gustavo da Costa Ferreira; Alexandre Umpierrez Amaral; Carlos Severo Dutra Filho; Clovis Milton Duval Wannmacher; Moacir Wajner

Book ID
113504406
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
596 KB
Volume
1291
Category
Article
ISSN
0006-8993

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## Abstract Patients affected by peroxisomal disorders commonly present neurologic dysfunction and brain abnormalities, whose neuropathology is poorly understood. Given that high sustained concentrations of pristanic acid (Prist) are found in the brain of these patients, it is conceivable that this