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Experimental Evidence for Major Histocompatibility Complex-Allele-Specific Resistance to a Bacterial Infection

✍ Scribed by Jakob Lohm, Mats Grahn, Åsa Langefors, Øivind Andersen, Arne Storset and Torbjörn von Schantz


Book ID
125055051
Publisher
The Royal Society
Year
2002
Tongue
English
Weight
763 KB
Volume
269
Category
Article
ISSN
0080-4649

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This report shows that lymphoid tissues of mice which have resolved a primary infection with Leishmania major contain parasite-specific major histocompatibility complex (MHC) class I-restricted cytolytic CD8+ T cell precusors that can be expanded after specific restimulation in vitro with syngeneic