Experimental evaluation of protective activity of Echinacea pallida against cisplatin toxicity

✍ Scribed by I. Mustea; I. D. Postescu; M. Tamas; T. D. Rasnita

• Book ID: 101287457
• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 100 KB
• Volume: 11
• Category: Article
• ISSN: 0951-418X
• DOI: 10.1002/(sici)1099-1573(199705)11:3<263::aid-ptr77>3.0.co;2-0

✦ Synopsis

The hydroalcohol standardized extract of E. pallida Nutt. given to mice p.o. in association with the i.p. administration of cisplatin exhibited protective effects expressed by a diminished loss and a faster recovery of the animal's body weight. Pretreatment with E. pallida also decreased cisplatin nephrotoxicity estimated from the level of kidney homogenate oxygen consumption.