Experimental designs to investigate capillary electrophoresis-electrospray ionization-mass spectrometry enantioseparation with the partial-filling technique

Chiral separation of local anaesthetics

Chiral separation of local anaesthetics by a capillary electrophoresis/partial filling technique coupled on-line to micro-electrospray mass spectrometry

✍ Jäverfalk, Emmy M.; Amini, Ahmad; Westerlund, Douglas; Andrén, Per E. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 253 KB 👁 2 views

A novel procedure for analysing chiral compounds is described in which a capillary electrophoresis/partial Ðlling technique was coupled on-line to micro-electrospray mass spectrometry. Enantiomers of bupivacaine and ropivacaine were separated using methyl-b-cyclodextrin, a non-volatile bu †er additi